At the onset of gastrulation, primitive streak morphogenesis that requires mitosis along the embryo midline, persists even with a disrupted bilateral cell flow.
Arya Y Nakhe, Prasanna K Dadi ... David A Jacobson
A mouse model of maturity-onset diabetes of the young illuminates that overactive TALK-1 channels limit β-cell calcium influx through membrane potential hyperpolarization, which blunts insulin secretion and causes glucose intolerance.