Computational and Systems Biology

Latest articles

1. 1. Genetics and Genomics
   2. Computational and Systems Biology

   Sequence characteristics and an accurate model of abundant hyperactive loci in the human genome

   Sanjarbek Hudaiberdiev, Ivan Ovcharenko
2. 1. Immunology and Inflammation
   2. Computational and Systems Biology

   Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

   Jan Stuchly, David Novak ... Tomas Kalina
3. 1. Computational and Systems Biology

   Improved clinical data imputation via classical and quantum determinantal point processes

   Skander Kazdaghli, Iordanis Kerenidis ... Philip Teare

   A new data imputation method that can be implemented quantumly allows for better and more reliable classifications.
4. 1. Neuroscience
   2. Computational and Systems Biology

   Testing the state-dependent model of subsecond time perception against experimental evidence

   Pirathitha Ravichandran-Schmidt, Joachim Hass
5. 1. Computational and Systems Biology

   Heritable epigenetic changes are constrained by the dynamics of regulatory architectures

   Antony M Jose

   A foundation for analyzing epigenetic changes within the context of regulatory architectures that enable heredity.
6. 1. Computational and Systems Biology
   2. Ecology

   Collaborative hunting in artificial agents with deep reinforcement learning

   Kazushi Tsutsui, Ryoya Tanaka ... Keisuke Fujii

   Collaborative hunting, characterized by the division of roles among predators, has emerged within a group of artificial agents through deep reinforcement learning.
7. 1. Computational and Systems Biology
   2. Developmental Biology

   The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults

   Arya Y Nakhe, Prasanna K Dadi ... David A Jacobson

   A mouse model of maturity-onset diabetes of the young illuminates that overactive TALK-1 channels limit β-cell calcium influx through membrane potential hyperpolarization, which blunts insulin secretion and causes glucose intolerance.
8. 1. Biochemistry and Chemical Biology
   2. Computational and Systems Biology

   The interplay between biomolecular assembly and phase separation

   Giacomo Bartolucci, Ivar S. Haugerud ... Christoph A. Weber
9. 1. Computational and Systems Biology

   Predicting metabolic modules in incomplete bacterial genomes with MetaPathPredict

   David Geller-McGrath, Kishori M Konwar ... Jason E McDermott

   MetaPathPredict is a novel bioinformatics tool that makes accurate predictions of KEGG module presence within highly incomplete bacterial genomes.
10. 1. Cell Biology
    2. Computational and Systems Biology

    Agent-based model demonstrates the impact of nonlinear, complex interactions between cytokines on muscle regeneration

    Megan Haase, Tien Comlekoglu ... Silvia S. Blemker